Sarcomas are rare tumours and, here, the first attempt at treatment largely determines the outcome: an inadequate first operation makes subsequent control of the disease much more difficult. This is why international guidelines recommend treatment at a centre with direct experience of sarcomas — with a multidisciplinary tumour board and histology review.
At Anadolu, sarcomas are managed by a team: surgical oncologist, orthopaedic oncologist, radiation oncologist and medical oncologist, alongside a specialist pathologist. For limb tumours, the aim is to remove the tumour while preserving the limb and its function.
Treatment methods at Anadolu
Wide-margin surgery
En bloc excision of the tumour with safety margins — this is the foundation of treatment. For limb tumours, the standard approach is limb preservation with reconstruction.
Radiotherapy
Given before or after surgery depending on the location and margins — it reduces the risk of local recurrence. Precise techniques that spare the surrounding tissues (IMRT/VMAT) are used.
Chemotherapy
In osteosarcoma and Ewing sarcoma, chemotherapy is an integral part of the protocol; in soft tissue sarcomas, it is used according to the subtype and risk.
Targeted therapy
GIST tumours are treated with tyrosine kinase inhibitors (TKIs) matched to the mutation profile; for certain subtypes, specific targeted options exist.
Treatment of metastases
Lung metastases are removed with surgery or radiosurgery (CyberKnife) — an active approach that prolongs survival.
Why international patients choose Anadolu
- Affiliation with Johns Hopkins Medicine — shared clinical protocols with one of the largest medical centres in the United States.
- JCI, ESMO and OECI accreditations — internationally recognised quality and patient safety.
- Multidisciplinary tumour boards — your treatment plan is decided not by a single doctor but by a team of specialists.
- Support in English — a coordinator and an interpreter at every step, from your first enquiry to discharge.
- A transparent cost estimate before you travel — you know the estimated cost of treatment in advance.
- Practical assistance — our team assists with travel and, where needed, visa formalities.
Specialist doctors
İbrahim Akmaz
Associate Professor of Orthopaedics and Traumatology
Orthopaedics and Traumatology
Mehmet Taner Özdemir
Orthopaedics and traumatology
Orthopaedics and Traumatology
Yeşim Yıldırım
Professor of Medical Oncology
Medical OncologyHow to start your treatment
Send your records
Reports, scans and test results — via the form, by email or WhatsApp.
The doctor’s opinion
A specialist will review your case free of charge within 48 hours.
Plan and cost estimate
You will receive the treatment plan and its estimated cost — before you travel.
Arrival and treatment
Transfers, accommodation and an interpreter — everything is arranged by the hospital.
Frequently asked questions — sarcoma
Why is it important to treat a sarcoma at a specialist centre?
Because the disease is rare: a correct biopsy, histology review and planning of the first operation require experience. A poorly planned first operation often cannot be put right.
Is it possible to keep the leg or arm?
In more than 90% of limb tumours — yes. Reconstructions and, if necessary, prostheses are used; amputation is now the exception.
I have been diagnosed with “sarcoma” — what should I send for a second opinion?
The histology report (if possible also the slides and blocks), an MRI of the area and a CT scan of the chest. Anadolu’s pathologists will review the diagnosis — the subtype often changes the plan.
How long does treatment take?
It depends on the protocol: surgery alone requires a stay of 10 to 14 days; protocols combining chemotherapy and radiotherapy last several months and can partly be continued closer to home.
Is GIST the same as a sarcoma?
GIST is a particular subtype of sarcoma of the digestive tract, treated with targeted tablets and surgery — when properly managed, its prognosis is very good.
Request a treatment plan and cost estimate
Free: a specialist will review your records within 48 hours.